More often the heartburn arises because of problems with the inferior sphincter of an esophagus - the ring located between a stomach and an esophagus. In the normality the sphincter is densely compressed. It is discovered only during transit of meal from an esophagus in a stomach, DOXYCYCLINE and then again occludes "hiluses". But there can be "breakage" of this remarkable mechanism. On the various causes (the genetical predilection, the tolerated diseases) the sphincter ceases to be closed densely, and the stomach maintenance gets to an esophagus. Together with the semidigested products bile and a hydrochloric acid gets to buy anafranil an esophagus. Caustic materials stimulate mucous an esophagus, and the heartburn begins. It often arises at the person who lays (especially on left to a side) or works, strongly bending forward (during washing, washing of a floor, work, on a kitchen garden). Sometimes the person should bend only to fasten laces on boots as in a mouth at once there are unpleasant sensations.